| Product name: | Human TIMP1 antigen |
|---|---|
| Synonym: | Human TIMP1 Antigen, Human TIMP1 recombinant protein,Human TIMP1 protein antigen, Human CLGI, EPA, EPO, HCI, TIMP, TIMP-1,TIMP metallopeptidase inhibitor 1, Antigen |
| Product Type: | Recombinant protein antigen |
| Product Category: | Tumor markers |
| Catalog: | AG10017 |
| Qty/Pack Size: | 100ug, 1mg |
| Format: | Purified Recombinant Antigen. |
| Source: | Human |
| Express Host: | Hek293 Cells |
| Purity: | >95% |
| Supplied In: | 10 mM Phosphate Buffer, 150 mM Sodium Chloride, pH 7.4 |
| Applications: | ELISA, Lateral Flow, CMIA |
| Storage: |
Short Term (≤ 2 weeks): 2-8°C. Long Term: -20°C. Avoid repeated freezing and thawing.
Recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Bulk packages canbeprovided as lyophilized powder which shipped with blue ice. |
| Construction: | A DNA sequence encoding the Human TIMP1 Protein was expressed with His-tag in C terminus. |
| Molecular Mass: | The protein of Human TIMP1 consists of 184 amino acids. |
| Biological Activity: | N/A |
| Endotoxin | N/A |
| Gene ID: | |
| Gene sequence: | NM_003254.3, Homo sapiens TIMP metallopeptidase inhibitor 1 (TIMP1), mRNA |
| Protein sequence: | NP_003245.1, metalloproteinase inhibitor 1 precursor [Homo sapiens] |
| Discription: | TIMP metallopeptidase inhibitor 1 is also known as TIMP1, a tissue inhibitor of metalloproteinases, is aglycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMPfamily.There are four members of the family, TIMP1,TIMP2,TIMP3 and TIMP4. TIMP1 is a glycoproteinwithamolecular mass of 28 kDa produced by a wide range of cell types. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is abletopromote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, theexpression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphicin human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in theopposite direction. |
| Sequence: |
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| SDS Page: | -- |
| Note: | This product is intended for research and manufacturing uses only. It is not a diagnostic device. The user assumes all responsibility for care, custody and control of the material, including its disposal, in accordance with all regulations. |
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TIMP-1 Product Infomation
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